Q.H. Ye (ESS), Y. Lau (ESS)
Extended-spetrum β-lactamases (ESBLs) producing Escherichia coli (E.coli) is an emerging major pathogen worldwide. It has the ability to hydrolyze and cause resistance to various types of newer β-lactamases antibiotics, including third generation cephalosporins and monobactams. Organisms that produce ESBLs remain an important reason for therapy failure with cephalosporin and have serious consequences for infection control. Those clinical microbiology laboratories detect and report ESBL-producing organism is therefore important. The objectives of this study were to determine the prevalence, genotype and clonal relationship of extended-spectrum β-lactamases (ESBLs) in 209 clinical Escherichia coli strains from Macao, China.